The Wilmington Fire Department said teams requested by state emergency management are deploying to locate the missing people.
Earlier, the National Weather Service Wilmington Office reported structural damage and power lines and urged people to avoid the area.
CNN has reached out to the Brunswick County Emergency Management Office for more information.
Storms will continue in the area, and tornadoes are still raging in eastern North Carolina, according to CNN meteorologist Michael Guy.
Areas north of Wilmington including the outer banks of Elizabeth City remain under guard until 1 p.m. 8, he said.
This is a story that is evolving and will be updated as more information becomes available.